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Join hosts Toni Okamoto and Paul Shapiro as they talk with some of the leading start-up entrepreneurs and titans of industry alike using their businesses to help solve the world’s most pressing problems.

Jan 15, 2020

How do people with ideas for businesses to save the world find cofounders? If you’re fashion designer Michalyn Andrews, you read journal articles by scientists doing awesome things in biotech, cold-email them to ask them to meet up, and make the proposal at a Starbucks. 

Her dream: to make real leather from cows to...


Jan 1, 2020

You’ve likely heard the story about the Jew who was said to have taken a small amount of fish and multiplied it to feed thousands. Well, in 2020, there’s another innovative Jew, Lou Cooperhouse, who is literally multiplying the fish—or at least their cells—in the hopes of again feeding the masses, and saving our...


Dec 15, 2019

Plastic is amazing at doing so many things—except going away. As the planet increasingly swims in humanity’s plastic garbage (nearly none of which gets recycled and virtually all of which will last for centuries), Lori Goff is betting that biotech will be part of the solution to creating functional plastic...


Dec 1, 2019

In the 29 previous episodes of this show you’ve heard about pork without pigs, milk without cows, diamonds without mining, and even wood without trees. Well, on this 30th episode, we’re exploring the brave new world of coffee without the bean.

Turns out that there’s a lot of deforestation for coffee growing, and...


Nov 15, 2019

What do  you get when you combine a Google leader, a dairy industry executive, and an engineer? Apparently, if you’re in Singapore, you get a new startup producing real cow’s milk-- without the cow: TurtleTree Labs.

Rather than trying to turn plants into milky beverages like many alt-dairy companies are, and rather...