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Join host Paul Shapiro as he talks with some of the leading start-up entrepreneurs and titans of industry alike using their businesses to help solve the world’s most pressing problems.

Dec 1, 2020

Most start-ups fail. Many that don’t fail still don’t have spectacular results. Chris Bryson, however, defied the odds by founding and running a company that was so successful Instacart acquired it for a reported $65 million.

Rather than retiring to a tropical beach with regular daiquiri service, Chris charted...


Oct 1, 2020

When this podcast was first launched in 2018, the very first guest was Whole Foods Market CEO and co-founder John Mackey. In that episode, we talked about his book Conscious Capitalism. Well, John has a new book out now, Conscious Leadership, and to commemorate our 50th episode, he rejoins the podcast for a second...


Sep 15, 2020

Think about how many plants there are: hundreds of thousands of different species. Yet when you look at plant-based meats, nearly all are made of one or more of just three of those plant species: soy, wheat, and pea. And there’s good reason for it: those plants are relatively cheap and plentiful, they taste good, and...


Sep 1, 2020

Think about how much metal you use in your life. Your phone. Your canned drinks. Your car.

Well, for every ounce of metal in our lives, there are several ounces of often-toxic sludge left behind from the extraction process at the mine. In other words, in a car there might be a ton of aluminum, and to get that...


Jun 1, 2020

If you’re a regular listener of the show, you may recognize the name of this episode’s guest since she’s been mentioned on at least two past episodes. Isha Datar is a cofounder of both Perfect Day and Clara Foods, companies respectively growing real dairy and egg proteins from microbes and which were the subjects...